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Myelofibrosis with myeloid metaplasia

1 OMIM reference -
4 associated genes
No signs/symptoms info

PROTEIN INTERACTIONS: 2

Metachondromatosis

1 OMIM reference -
1 associated gene
10 signs/symptoms

Myelofibrosis with myeloid metaplasia

Metachondromatosis

CALR	(UniProt - OMIM)		PTPN11	(UniProt - OMIM)
JAK2	(UniProt - OMIM)
MPL	(UniProt - OMIM)
TET2	(UniProt - OMIM)


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	JAK2 MPL	(0.96) (0.52)	PTPN11 PTPN11

Citations in the biomedical literature:

Myelofibrosis with myeloid metaplasia		Metachondromatosis
	Synonym(s): - Agnogenic myeloid metaplasia - Idiopathic myelofibrosis - Myelosclerosis with myeloid metaplasia - Primary myelofibrosis		Synonym(s): (no synonyms)

	Classification (Orphanet): - Rare hematologic disease - Rare oncologic disease		Classification (Orphanet): - Rare bone disease - Rare developmental defect during embryogenesis - Rare genetic disease

	Classification (ICD10): - Neoplasms -		Classification (ICD10): - Congenital malformations, deformations and chromosomal abnormalities -

	Epidemiological data: (no data available)		Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: childhood Average age of death: normal Type of inheritance: autosomal dominant

	External references: 1 OMIM reference - No MeSH references		External references: 1 OMIM reference - No MeSH references

Metachondromatosis
	Very frequent - Autosomal dominant inheritance - Bone pain - Cranial nerves palsy - Enchondroses - Epiphyseal anomaly - Exostoses - Metaphyseal anomaly - Osteonecrosis / bone infarction - Pelvis anomaly / Narrow / broad iliac wings / pubis abnormality - Periarticular tissue anomaly / extraarticular calcifications
Myelofibrosis with myeloid metaplasia
(no data available)